Severe Atopic Eczema: Exploring the Link Between Skin Barrier Dysfunction and Bone Density

Abstract

Vitamin D deficiency is a common factor in the pathogenesis of both rickets and atopic eczema. Vitamin D
is necessary for calcium and phosphorus absorption, which are essential for mineralization, and it is also
essential for immune and allergic responses. This case report will highlight the relationship between atopic
eczema and rickets and the approach to managing both conditions when they occur simultaneously in
children.
We report a 4-year -old boy who presented to our clinic with severe atopic eczema, hypocalcemic tetany,
rickets and developmental delay and was successfully managed.
Keywords: Atopic eczema, Rickets, Skin Barrier Dysfunction, Bone density, developmental delay