A Case of Pigmented Verrucous Bowen's Disease in a Nigerian Woman
Abstract
Bowen's disease also known as squamous cell carcinoma (SCC) in situ is an uncommon premalignant lesion that
affects both the skin and mucous membranes. Several risk factors have been identified including chronic
exposure to ultraviolet radiation, immunosuppression, and exposure to some subtypes of human papilloma
virus infection amongst others. The disease may be a differential for certain conditions like malignant
melanoma and superficial basal cell carcinoma hence a histological diagnosis is essential in its diagnosis.
Treatment options include topical, surgical and non-surgical ablative techniques. We report a case of Bowen's
disease in a 61 year old Nigerian female trader who was managed successfully with topical 5 Fluorouracil cream.
Key words: Bowen's disease, squamous cell carcinoma in situ, risk factors, differential, treatment options.
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